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Age, genetics, and existing health status all affect conversion rates
Am J Clin Nutr 1981
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M.BartolomucciA.BuwaldaB.de BoerS
For example, rs13429103 at 2p25.1, located near RNF144A-LOC339788 , demonstrated a borderline interaction with smoking ( P = 2.18 10)
Glutathione in Human Plasma: Decline in Association with Aging, Age-Related Macular Degeneration, and Diabetes
Then layer in the technical barriers to generic entry (bioequivalence complexity, limited generic manufacturer capability, FDA product-specific guidance requirements) to assess the probability and magnitude of price erosion for each year of the patent window
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